PectaSol-C




under construction



(1) Integr Cancer Ther. 2013 Mar;12(2):145-52. doi: 10.1177/1534735412442369. Epub 2012 Apr 24.
Synergistic and additive effects of modified citrus pectin with two polybotanical compounds, in the suppression of invasive behavior of human breast and prostate cancer cells.
Jiang J, Eliaz I, Sliva D.
Indiana University Health, Indianapolis, IN, USA.

(2) Cell Biol Int. 2012 Jul;36(7):601-10. doi: 10.1042/CBI20110309.
Combination effect of PectaSol and Doxorubicin on viability, cell cycle arrest and apoptosis in DU-145 and LNCaP prostate cancer cell lines.
Tehranian N, Sepehri H, Mehdipour P, Biramijamal F, Hossein-Nezhad A, Sarrafnejad A, Hajizadeh E.
Animal Biology Department, School of Biology, University College of Sciences, University of Tehran, PO Box 1415, Tehran, Islamic Republic of Iran.

(3) Integr Cancer Ther. 2010 Jun;9(2):197-203. doi: 10.1177/1534735410369672. Epub 2010 May 11.
PectaSol-C modified citrus pectin induces apoptosis and inhibition of proliferation in human and mouse androgen -dependent and -independent prostate cancer cells.
Yan J, Katz A.
Department of Urology, Columbia University Medical Center, 1130 St. Nicholas Ave., New York, NY 10032, USA.

(4) Altern Ther Health Med. 2008 Jul-Aug;14(4):34-8.
The role of modified citrus pectin as an effective chelator of lead in children hospitalized with toxic lead levels.
Zhao ZY, Liang L, Fan X, Yu Z, Hotchkiss AT, Wilk BJ, Eliaz I.
Department of Medicine, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Republic of China.

(5) Forsch Komplementmed. 2007 Dec;14(6):358-64. doi: 10.1159/0000109829. Epub 2007 Dec 12.
Integrative medicine and the role of modified citrus pectin/alginates in heavy metal chelation and detoxification--five case reports.
Eliaz I, Weil E, Wilk B.
Amitabha Medical Clinic and Healing Center Sebastopol, CA 95472, USA.

(6) Phytother Res. 2006 Oct;20(10):859-64.
The effect of modified citrus pectin on urinary excretion of toxic elements.
Eliaz I, Hotchkiss AT, Fishman ML, Rode D.
Amitabha Medical Clinic and Healing Center, 7064 Corline Ct. Ste A, Sebastopol, CA 95472, USA.

(7) Food Funct. 2013 Jun;4(6):960-71. doi: 10.1039/c3fo30350k. Epub 2013 May 14.
Comparative studies on the anti-tumor activities of high temperature- and pH-modified citrus pectins.
Hao M, Yuan X, Cheng H, Xue H, Zhang T, Zhou Y, Tai G.
School of Life Science, Northeast Normal University, 5268 Renmin Street, 130024 Changchun, Jilin Province, People's Republic of China

(8) http://www.econugenics.com

(9) Glycoconj J. 2012 May;29(4):159-65. doi: 10.1007/s10719-012-9382-5. Epub 2012 May 7.
Analysis of the neutral polysaccharide fraction of MCP and its inhibitory activity on galectin-3.
Gao X, Zhi Y, Zhang T, Xue H, Wang X, Foday AD, Tai G, Zhou Y.
School of Life Sciences, Northeast Normal University, 5268 Renmin Street, Changchun, 130024, People's Republic of China.

(10) Cell Death Dis. 2013 Aug 1;4:e753. doi: 10.1038/cddis.2013.277.
The significance of galectin-3 as a new basal cell marker in prostate cancer.
Wang Y, Balan V, Gao X, Reddy PG, Kho D, Tait L, Raz A.
Department of Oncology, Karmanos Cancer Institute, School of Medicine, Wayne State University, Detroit, MI 48201, USA.

(11) Cancer Biol Ther. 2013 Aug 5;14(10). [Epub ahead of print]
Galectin-3 inhibition sensitizes human renal cell carcinoma cells to arsenic trioxide treatment.
Xu Y, Gu X, Gong M, Guo G, Han K, An R.
Department of Urological Surgery; The Affiliated Tumor Hospital of Harbin Medical University; Heilongjian, PR China. Case Rep Oncol. 2013 Jul 3;6(2):343-9. doi: 10.1159/000353574. Print 2013 May.

(12) Case Rep Oncol. 2013 Jul 3;6(2):343-9. doi: 10.1159/000353574. Print 2013 May.
The Role of Galectin-3 as a Marker of Cancer and Inflammation in a Stage IV Ovarian Cancer Patient with Underlying Pro-Inflammatory Comorbidities.
Amitabha Medical Clinic and Healing Center, Santa Rosa, Calif., USA.

(13) Swiss Med Wkly. 2004 Jan 10;134(1-2):24-7.
Reducing the 137Cs-load in the organism of "Chernobyl" children with apple-pectin.
Nesterenko VB, Nesterenko AV, Babenko VI, Yerkovich TV, Babenko IV.
Belrad Institute of Radiation Safety, Charity House, 11 Staroborisovsky Trakt, 220114 Minsk, Republic of Belarus.

(14) Activation of Human T-Helper/Inducer Cell, T-Cytotoxic Cell, B-Cell, and Natural Killer (NK)-Cells and induction of Natural Killer Cell Activity against K562 Chronic Myeloid Leukemia Cells with Modified Citrus Pectin.
Cheppail Ramachandran1*, Barry J Wilk2, Arland Hotchkiss34, Hoa Chau3, Isaac Eliaz2 and Steven J Melnick15
1 Dharma Biomedical LLC, Miami, FL, 33156, USA
2 Econugenics, Inc., Santa Rosa CA, 95407, USA
3 U.S. Department of Agriculture, USA
4 Agricultural Research Service, Eastern Regional Research Center, 600 E. Mermaid Lane, Wyndoor, PA 19038, USA
5 Department of Pathology, Miami Children's Hospital, Miami, FL 33155, USA

(15) Clinical Medicine: Oncology 2007:I 73-80
Clinical Benefit in Patients with Advanced Solid Tumors Treated with Modified Citrus Pectin: A Prospective Pilot Study.
Marc Azémar1, Bernd Hildenbrand1, Brigitte Haering1, Manfred E. Heim2 and Clemens Unger1
1Department of Clinical Oncology at the Tumor biology Center at the Albert-Ludwigs-University in Freiburg, Germany. 2Sonnenberg-Klinik, Bad Sooden-Allendorf, Germany.

(16) http://www.mayoclinic.com/health/chelation-therapy/MY00159/DSECTION=risks

(17) Prostate Cancer Prostatic Dis. 2003;6(4):301-4.
Modified citrus pectin (MCP) increases the prostate-specific antigen doubling time in men with prostate cancer: a phase II pilot study.
Guess BW, Scholz MC, Strum SB, Lam RY, Johnson HJ, Jennrich RI.
Prostate Oncology Specialist, Marina del Rey, California 90292, USA.

(18) The Encyclopedia of Natural Medicine, 3rd Edition
Michael T. Murray, N.D.
Joseph Pizzorno, N.D.
Atria books, 2012

(19) Glycobiology. 2013 Jun;23(6):654-63. doi: 10.1093/glycob/cwt006. Epub 2013 Feb 19.
Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice.
MacKinnon AC, Liu X, Hadoke PW, Miller MR, Newby DE, Sethi T.
Scottish Centre for Regenerative Medicine, SCRM Building, University of Edinburgh, Edinburgh Bioquarter, 5 Little France Drive, Edinburgh EH16 4UU, UK.

(20) Clin Cardiol. 1988 Sep;11(9):597-600.
Grapefruit pectin inhibits hypercholesterolemia and atherosclerosis in miniature swine.
Baekey PA, Cerda JJ, Burgin CW, Robbins FL, Rice RW, Baumgartner TG.
Department of Medicine, University of Florida College of Medicine, Gainesville, USA.

(21) Circulation. 1994 Mar;89(3):1247-53.
Inhibition of atherosclerosis by dietary pectin in microswine with sustained hypercholesterolemia.
Cerda JJ, Normann SJ, Sullivan MP, Burgin CW, Robbins FL, Vathada S, Leelachaikul P.
Department of Medicine, University of Florida College of Medicine, Gainesville, USA.

(22) http://www.dreliaz.org/mpc-hearthealth/

(23) Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):67-75. doi: 10.1161/ATVBAHA.112.300569. Epub 2012 Nov 1.
Galectin-3 mediates aldosterone-induced vascular fibrosis.
Calvier L, Miana M, Reboul P, Cachofeiro V, Martinez-Martinez E, de Boer RA, Poirier F, Lacolley P, Zannad F, Rossignol P, López-Andrés N.
Inserm, U961, Faculty of Medicine, Université de Lorraine, Vandoeuvre-lès-Nancy, France.